Mechanical circulatory support refers to the use of mechanical devices to assist or replace the function of the heart in pumping blood throughout the body. This technology is often used in patients with severe heart failure or other cardiac conditions that are at risk of cardiogenic shock or end-stage heart failure. Mechanical circulatory support devices can be temporary or permanent solutions and can include devices such as ventricular assist devices (VADs), total artificial hearts, and extracorporeal membrane oxygenation (ECMO). These devices help to improve blood flow, reduce strain on the heart, and provide support until the heart can recover or until a heart transplant can be performed. Research in this area focuses on improving the design and function of these devices, optimizing patient outcomes, and expanding the use of mechanical circulatory support in different patient populations.